Over-the-counter cold and flu medicines can affect your heart

As the cold and flu season continues this year, it is important to be aware that many of the most commonly used over-the-counter (OTC) remedies for congestion, aches, pains, and low-grade fevers contain medicines that can have harmful effects on the cardiovascular system. Chief among these medications are nonsteroidal anti-inflammatory drugs (NSAIDs) and decongestants. NSAIDs and your heart Certain NSAIDs are associated with a small increase in the relative risk for developing a heart attack, stroke, heart failure, atrial fibrillation, increased blood pressure, and blood clots. NSAIDs relieve pain and inflammation by inhibiting an enzyme called COX that produces molecules called prostaglandins. However, this enzyme also has additional important effects throughout the body, which may impact cardiovascular risk. For example, the inhibition of

From https://www.health.harvard.edu/blog/over-the-counter-cold-and-flu-medicines-can-affect-your-heart-2019032016220

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