T Cell Senescence Is Involved in the Disruption of Glucose Metabolism in Type 2 Diabetes

Cellular senescence is an important contributing cause of aging. Senescent cells accumulate with age and secrete a potent mix of molecules and vesicles, the senescence associated secretory phenotype. This disrupts tissue function in a range of ways, and produces chronic inflammation that accelerates the progression of all of the common age-related conditions. All forms of cell in the body appear to be capable of senescence, and the cells of the immune system are no exception. With advancing age, an increasing number of T cells of the adaptive immune system become senescent, producing the same damaging secretions. Exactly what damage is done by senescent T cells? Firstly, it appears that they contribute to autoimmunity – which is very interesting in light of other work showing that senescent cells

From https://www.fightaging.org/archives/2019/03/t-cell-senescence-is-involved-in-the-disruption-of-glucose-metabolism-in-type-2-diabetes/

from
https://healthnews010.wordpress.com/2019/03/21/t-cell-senescence-is-involved-in-the-disruption-of-glucose-metabolism-in-type-2-diabetes/

from https://karlfletcher.blogspot.com/2019/03/t-cell-senescence-is-involved-in.html

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https://karlfletcher1.tumblr.com/post/183601700148